EBP Compendium: Summary of Systematic Review
Supported in part by a grant from the National Institutes of Health
Botox Treatment in Adductor Spasmodic Dysphonia: A Meta-Analysis
Boutsen, F., Cannito, M. P., et al.
(2002).
Journal of Speech, Language, and Hearing Research, 45, 469-481.
Indicators of Review Quality:
|
The review addresses a clearly focused question
| Yes |
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Criteria for inclusion of studies are provided
| Yes |
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Search strategy is described in sufficient detail for replication
| No |
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Included studies are assessed for study quality
| No |
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Quality assessments are reproducible
| No |
Description: This is a descriptive review and meta-analysis of studies assessing the effects of botulinum toxin type A for the treatment of adductor spasmodic dysphonia. Although involvement of speech-language pathology was not reported, a number of short term and long term perception outcomes were included.
Question(s) Addressed:
Question not specifically stated.
Population: Individuals with adductor spasmodic dysphonia.
Intervention/Assessment: Injection of botulinum toxin
Number of Studies Included: 30
Years Included: 1988-1999
Findings:
Conclusions:
- Treatment
- Voice
- "Although the data indicate moderate overall improvement as a result of Botulinum toxin treatment, they also suggest significant variation across patients, measurements, and treatment conditions" (p. 469).
- A number of methodological limitations and lack of standardization in treatment protocol warrant caution when interpreting the results.
Keywords: Spasmodic Dysphonia, Voice Disorders
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Added to Compendium: December 2011