Summary of the Systematic Review

Article Citation

Treatments for Ankyloglossia and Ankyloglossia With Concomitant Lip-Tie

Francis, D. O., Chinnadurai, S., et al. (2015).
Rockville (MD): Agency for Healthcare Research and Quality, (Comparative Effectiveness Review No. 149. (Prepared by the Vanderbilt Evidence-based Practice Center under Contract No. 290-2012-00009-I.) AHRQ Publication No. 15-EHC011-EF)
Go to Article

Sponsoring Body

Agency for Healthcare Research and Quality

Article Quality Ratings

Read about Our Rating Process

Indicators of Review Quality

  • Yes The review states a clearly focused question/aim.
  • Yes Criteria for inclusion of studies are provided.
  • Yes Search strategy described in sufficient detail for replication.
  • Yes Included studies are assessed for study quality.
  • Yes Quality assessments are reproducible.
  • Yes Characteristics of the included studies are provided.

Article Details

Description

This is a systematic review of randomized controlled trials, cohort studies, case series, and case reports investigating surgical and non-surgical treatments in children (newborn to 18 years of age) with ankyloglossia or ankyloglossia with concomitant lip-tie.

Questions/Aims Addressed

This review addresses the following aims to identify

  • Benefits of treatments intended to improve breastfeeding outcomes;
  • Benefits of treatments intended to prevent, diminish, or remedy attributable feeding ramifications (e.g., difficulty bottle-feeding);
  • Benefits of treatments intended to prevent, diminish, or remedy other attributable ramifications (e.g., articulation disorders, oral and oropharyngeal dysphagia);
  • Benefits of treatments intended to prevent/address social concerns  related to tongue mobility (i.e., speech, oral hygiene, excessive salivation, kissing, spitting while talking, self-esteem);
  • Benefits of simultaneous treatment of akyloglossia and concomitant lip-tie intended to improve breastfeeding, articulation, orthodontic/dental, and other feeding outcomes;
  • Relative benefits of treating only ankyloglossia when lip-tie is also diagnosed; and
  • Harms of treatment for ankylogossia or ankyloglossia with concomitant lip-tie in children.

Population

Children, newborn through 18 years of age, with ankyloglossia or ankyloglossia with concomitant lip-tie

Intervention/Assessment

Surgical and non-surgical treatments for ankyloglossia or ankyloglossia with concomitant lip-tie

Number of Studies Included

58

Years Included

From database inception up to August 2014

Evidence Ratings for This Document

The strength of evidence is classified into one of four categories as stipulated in The Effective Health Care Program's update of "Methods Guide for Effectiveness and Comparative Effectiveness Reviews" (Berkman et. al, 2008):

  • High: Authors are very confident the estimate of effect is close to the true effect for this outcome (i.e., evidence has few or no deficiencies, stable findings).
  • Moderate: Authors are moderately confident that the estimate of effect is close to the true effect for this outcome (i.e., evidence has some deficiencies, findings are likely stable).
  • Low: Authors have limited confidence that the estimate of effect is close to the true effect for this outcome (i.e., evidence has major or numerous deficiencies, additional evidence needed).
  • Insufficient: Authors have no evidence, are unable to estimate an effect, or have no confidence in the estimate of effect for this outcome (Table 5; p. 15).

Conclusions from This Systematic Review

What are Conclusions?

Go to Map

Treatment

No evidence was found to assess non-surgical treatments in children with ankyloglossia or ankyloglossia with a concomitant tight labial frenulum (lip-tie).

Keywords: Early Intervention, Early Intervention, Ankyloglossia

Go to Map

Treatment

No evidence was found to assess non-surgical treatments in children with ankyloglossia or ankyloglossia with a concomitant tight labial frenulum (lip-tie).

Keywords: Early Intervention, Early Intervention, Ankyloglossia

Notes on This Article

Data from this systematic review were also published in the following articles:

  • Francis, D. O., Krishnaswami, S., et al. (2015). Treatment of Ankyloglossia and Breastfeeding Outcomes: A Systematic Review. Pediatrics, 135(6), e1458-e1466. doi:10.1542/peds.2015-0658 
  • Chinnadurai, S., Francis, D. O., Epstein, R. A., Morad, A., Kohanim, S., & McPheeters, M. (2015). Treatment of Ankyloglossia for Reasons Other Than Breastfeeding: A Systematic Review. Pediatrics, 135(6), e1467-e1474. doi:10.1542/peds.2015-0660

Our Partners