Summary of the Systematic Review
Toddler Screening for Autism Spectrum Disorder: A Meta-Analysis of Diagnostic Accuracy
Sánchez-García, A. B., Galindo-Villardón, P., et al. (2019).
Journal of Autism and Developmental Disorders, 49(5), 1837-1852.
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Ministry of Education, Spain; Fulbright Commission Spain
Indicators of Review Quality
- Yes The review states a clearly focused question/aim.
- Yes Criteria for inclusion of studies are provided.
- Yes Search strategy described in sufficient detail for replication.
- Yes Included studies are assessed for study quality.
- No Quality assessments are reproducible.
- Yes Characteristics of the included studies are provided.
Quality Rating Notes
Study Quality: Only aggregate results were provided.
This is a meta-analysis of diagnostic studies investigating Level 1 screening tools for autism spectrum disorder in toddlers.
The following objectives were addressed:
- evaluate the accuracy of different tools to screen for autism spectrum disorder in toddlers; and
- calculate the pooled psychometric properties of the different tools to evaluate the tools' effectiveness.
Toddlers, aged 14 months to 36 months
Level 1 screening tools
Number of Studies Included
January 1992 to April 2015
Conclusions from This Systematic Review
What are Conclusions?
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Results of the meta-analysis demonstrated that level 1 screening tools for autism spectrum disorder (ASD), had a pooled sensitivity of 0.72 (95% CI 0.61–0.81) and pooled specificity of 0.98 (95% CI 0.97–0.99). These results indicated that level 1 ASD screening tools, such as the Modified Checklist for Autism in Toddlers (M-CHAT), Checklist for Autism in Toddlers (CHAT), and Screening Tool for Autism in Toddlers and Young Children (STAT), were accurate at detecting the presence of ASD (sensitivity) and highly accurate at detecting a lack of presence of ASD (specificity).