Table 1. Levels of evidence for studies of treatment efficacy, ranked according to quality and credibility from highest/most credible (Ia) to lowest/least credible (IV) (adapted from the Scottish Intercollegiate Guideline Network, www.sign.ac.uk).

Level Description
Ia Well-designed meta-analysis of >1 randomized controlled trial
Ib Well-designed randomized controlled study
IIa Well-designed controlled study without randomization
IIb Well-designed quasi-experimental study
III Well-designed nonexperimental studies, i.e., correlational and case studies
IV Expert committee report, consensus conference, clinical experience of respected authorities